Chemotaxonomic Characterization and in-Vitro Antimicrobial and Cytotoxic Activities of the Leaf Essential Oil of Curcuma longa Grown in Southern Nigeria
نویسندگان
چکیده
Curcuma longa (turmeric) has been used in Chinese traditional medicine and Ayurvedic medicine for many years. METHODS The leaf essential oil of C. longa from southern Nigeria was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). The essential oil was screened for in vitro antibacterial, antifungal, and cytotoxic activities. The major components in C. longa leaf oil were ar-turmerone (63.4%), α-turmerone (13.7%), and β-turmerone (12.6%). A cluster analysis has revealed this to be a new essential oil chemotype of C. longa. The leaf oil showed notable antibacterial activity to Bacillus cereus and Staphylococcus aureus, antifungal activity to Aspergillus niger, and cytotoxic activity to Hs 578T (breast tumor) and PC-3 (prostate tumor) cells. The ar-turmerone-rich leaf essential oil of C. longa from Nigeria has shown potent biological activity and therapeutic promise.
منابع مشابه
CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITIES OF ESSENTIAL OILS OF SOME CONIFEROUS PLANTS CULTIVATED IN EGYPT
Family Cupressaceae is the largest coniferous plant family. Essential oils of many species belonging to family Cupressaceae are known to have several biological activities specially antimicrobial activity. The essential oils from aerial parts of Calocedrus decurrens Torr., Cupressus sempervirens stricta L. and Tetraclinis articulata (Vahl) Mast. were prepared by hydrodistillation. The chemical ...
متن کاملComposition and Antimicrobial Activity of the Essential Oil from Leaves of Curcuma longa L. Kasur Variety
The essential oil from the leaves of Curcuma longa L. Kasur variety grown in Pakistan was extracted by hydro-distillation. Chemical constituents of the essential oil were identified by gas chromatography/mass spectrometry. The chromatographic analysis of oil showed 25 constituents, out of which nine chemical constituents were identified. The eucalyptol (10.27%) was the major component of the es...
متن کاملNeuropharmacological profile and chemical analysis of fresh rhizome essential oil of Curcuma longa (turmeric) cultivated in Southwest Nigeria
BACKGROUND Curcuma longa (turmeric) is commonly used as spice and also used to treat fever, cough and febrile convulsions in Nigeria. This study determined the chemical composition of the essential oil of C. longa and evaluated its neuropharmacological activity in mice. METHODS Essential oil of C. longa (EOCL) fresh rhizome was obtained by hydrodistillation and its chemical composition determ...
متن کاملCHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITIES OF ESSENTIAL OILS OF SOME CONIFEROUS PLANTS CULTIVATED IN EGYPT
Family Cupressaceae is the largest coniferous plant family. Essential oils of many species belonging to family Cupressaceae are known to have several biological activities specially antimicrobial activity. The essential oils from aerial parts of Calocedrus decurrens Torr., Cupressus sempervirens stricta L. and Tetraclinis articulata (Vahl) Mast. were prepared by hydrodistillation. The chemical ...
متن کاملChemical Composition of Rhizome Essential Oil of Curcuma longa L. Growing in North Central Nigeria
Pulverized rhizome of Curcuma longa on hydrodistilation, afforded oil in the yield of 1.24% v/w. The oil was investigated by GC and GC/MS. Hydrocarbon monoterpenes (46.9%) constituted bulk of the oil. The major constituents of the oil were, $-bisabolene (13.9%), trans-ocimene (9.8%), myrcene (7.6%), 1,8-cineole (6.9%), "-thujene (6.7%) and thymol (6.4%). Key word: Index: curcuma longa % Zingibe...
متن کامل